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ARIVAC-4

project name: Effectiveness of an 11-valent pneumococcal conjugate vaccine in preventing radiologically confirmed pneumonia in the Philippines

initiating country: The European Union

Framework Programme: FP5 programme area: INCO II – International Role of Community Research

contract/proposal/call number: ICA4-CT-2002-10062

status: completed

start date: January 2002 duration: 24 months projected finish date: January 2004

Keywords

keywords: Economic Aspects; Coordination; Cooperation; Scientific Research

Project Budget

total budget: € 2,982,652

Participants

Note that the follow people may not represent the full extent of the consortium. FEAST has tried to identify the Australian participants, and their collaborators (or coordinator), within the project. Also note that Australian participation may not necessarily be on a formal level.

name	organisation	state or country
	USyd	NSW, Australia
Prof Ian Riley	UQ	QLD, Australia

Further information

summary:

The general objective of the research is to find an effective primary prevention for a significant fraction of serious acute respiratory infections (ART), especially of severe ARI and related severe disease, in infants and children in developing countries. This can be achieved by studying the effectiveness of the 11-valet pneumococcal conjugate vaccine (11PCV) in preventing childhood pneumonia in the Philippines within a population-based randomised, placebo-controlled, blinded study . Other scientific questions, including transmission of pneumococci, will be addressed in nested studies and a specific household carriage study in Indonesia. The minimum sample size of 12 190 children to be enrolled within 3.5 years time is calculated on the basis of the primary hypothesis. An interim analysis is planned at end of 3rd year. The final results within 5 years will be directly and immediately applicable to countries in the South-East and East Asian region, and more widely to the large and growing number of developing countries with a moderate infant mortality rate of 40-60 / 1 000 live births.

Coordinator

Organization name: NATIONAL PUBLIC HEALTH INSTITUTE
Contact person	Address
Name: Hanna NOHYNEK (Dr)	DEPARTMENT OF VACCINOLOGY 166,Mannerheimintie 166 00300 HELSINKI SUOMI/FINLAND Region: MANNER-SUOMI UUSIMAA
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Organization name: NATIONAL PUBLIC HEALTH INSTITUTE
Contact person	Address
Name: Jaakko PENTTINEN (Mr.)	DEPARTMENT OF VACCINOLOGY 166,Mannerheimintie 166 00300 HELSINKI SUOMI/FINLAND Region: MANNER-SUOMI UUSIMAA
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Project Details

Start date: 2002-01-01	End date: 2003-12-31
Duration: 24 months	Project Reference: ICA4-CT-2002-10062
Project cost: 2982652 EURO	Project Funding: 2000000 EURO
Programme Acronym: INCO 2	Programme type: Fifth Framework Programme
Subprogramme Area: Research for development	Contract type: Cost-sharing contracts
Subject index: Economic Aspects, Coordination, Cooperation, Scientific Research
Other Indexes:

Other participants

Organization: AVENTIS PASTEUR SA
Contact person	Address
Name: ESKOLA, Juhani (PROF.)	58,Avenue Pont Pasteur, 2 69007 LYON FRANCE Region: CENTRE-EST RHÔNE-ALPES Rhône
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Organization: AVENTIS PASTEUR SA
Contact person	Address
Name: FEROLDI, Emmanuel (Dr)	58,Avenue Pont Pasteur, 2 69007 LYON FRANCE Region: CENTRE-EST RHÔNE-ALPES Rhône
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Organization: IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
Contact person	Address
Name: COX, Lynne (Mrs)	IMPERIAL COLLEGE SCHOOL OF MEDICINE Norfolk Place W2 1PG LONDON UNITED KINGDOM Region: SOUTH EAST (UK) GREATER LONDON
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Organization: IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
Contact person	Address
Name: LEVIN, Michael (Dr)	IMPERIAL COLLEGE SCHOOL OF MEDICINE Norfolk Place W2 1PG LONDON UNITED KINGDOM Region: SOUTH EAST (UK) GREATER LONDON
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Organization: PADJADJARAN UNIVERSITY
Contact person	Address
Name: KARTASASMITAS, Cissy (Dr)	SCHOOL OF MEDICINE JL. Pasirkaliki 190 40161 BANDUNG Region:
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Organization: PADJADJARAN UNIVERSITY
Contact person	Address
Name: PANIGORO, Ramdan (Dr.)	SCHOOL OF MEDICINE JL. Pasirkaliki 190 40161 BANDUNG Region:
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Organization: RESEARCH INSTITUTE FOR TROPICAL MEDICINE
Contact person	Address
Name: LUCERO, Marilla (Dr)	ARI - ACUTE RESPIRATORY INFECTION STUDY GROUP Filinvest Corporate City 1770 MUNTINLUPA CITY Region:
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Organization: RESEARCH INSTITUTE FOR TROPICAL MEDICINE
Contact person	Address
Name: OLVEDA, Remigio (Dr.)	ARI - ACUTE RESPIRATORY INFECTION STUDY GROUP Filinvest Corporate City 1770 MUNTINLUPA CITY Region:
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Organization: UNIVERSITY OF QUEENSLAND
Contact person	Address
Name:	AUSTRALIAN CENTRE FOR INTERNATIONAL AND TROPICAL HEALTH AND NUTRITION Herston Road Herston 4006 BRISBANE Region:
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Organization: UNIVERSITY OF SYDNEY
Contact person	Address
Name:	NHMRC CLINICAL TRIALS CENTRE Mallett Street 88, Level 5, Building F 2050 CAMPERDOWN Region:
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Sources: European Commission

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