There is now compelling evidence that the agent causing variant CJD (cud) is identical to that causing bovine spongiform encephalopathy. The future numbers of cases that may occur in European countries cannot be predicted. It is essential to monitor this potential outbreak and to identify risk factors for the development of cud. Assay systems to test for the presence of disease-associated prionprotein in peripheral blood have been developed and it is essential to evaluate the sensitivity and specificity of these tests in the identification of clinical and preclinical infection. The validation of such a test would have profound implications for the study of CJD epidemiology and for public health and a large series of cases is required. This proposal addresses both these objectives through the co-ordination and harmonisation of national CJD surveillance projects and in validating novel blood assay systems.
| Coordinator |
| Organization name: University of Edinburgh | |
| Contact person | Address |
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Name: Robert |
Old College South Bridge EH1 1HN Edinburgh UNITED KINGDOM Region: SCOTLAND BORDERS-CENTRAL-FIFE-LOTHIAN-TAYSIDE Lothian |
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| Fax: +45-45-169292 | |
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| Other participants |
| Organization: CREUTZFELDT-JAKOB DISEASE SURVEILLANCE SYSTEM | |
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Name: |
LABORATORY CENTRE FOR DISEAS CONTROL Tunney’s Pasture K1A OL2 OTTAWA Region: |
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| Organization: ERASMUS UNIVERSITEIT ROTTERDAM | |
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Name: |
FACULTY OF MEDICINE AND HEALTH SCIENCES 50,Dr. Molewaterplein 50 3015 GE ROTTERDAM NEDERLAND Region: WEST-NEDERLAND ZUID-HOLLAND Groot-Rijnmond |
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| Organization: GEORG-AUGUST-UNIVERSITY GOETTINGEN | |
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Name: |
KLINIK UND POLIKLINIK FUER NEUROLOGIE Robert-Koch-Strasse 40 37075 GOETTINGEN DEUTSCHLAND Region: NIEDERSACHSEN BRAUNSCHWEIG Göttingen |
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| Organization: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE | |
| Contact person | Address |
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Name: |
U 360 - RECHERCHE EPIDEMIOLOGIQUE EN NEUROLOGIE ET PSYCHOPATHOLOGIE Hopital de la Salpetriere, 47, Boulevard de l’Hop 75651 PARIS FRANCE Region: ÎLE DE FRANCE Paris |
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| Organization: INSTITUTE OF HEALTH CARLOS III | |
| Contact person | Address |
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Name: |
SUBDIRECTION GENERAL EPIDEMIOLOGIA Y CENTROS NACIONALES DE SALUD PUBLICA Calle Sinesio Delgardo 6 28029 MADRID ESPAÑA Region: COMUNIDAD DE MADRID |
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| Organization: INSTITUTE OF PREVENTIVE AND CLINICAL MEDICINE | |
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Name: |
DEPARTMENT OF SLOW VIRUS INFECTIONS 14,Limbova 14 833 01 BRATISLAVA SLOVENSKA REPUBLIKA Region: |
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| Organization: ISTITUTO SUPERIORE DI SANITA | |
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Name: |
VIROLOGY LABORATORY Viale Regina Elena 299 00161 ROMA ITALIA Region: LAZIO Roma |
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| Organization: THE UNIVERSITY OF MELBOURNE | |
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Name: |
DEPARTMENT OF PATHOLOGY Grahan street 3010 PARKVILLE VICTORIA Region: |
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| Organization: UNIVERSITY OF VIENNA | |
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Name: |
INSTITUTE OF NEUROLOGY Waehringer Guertel 18-20 1097 WIEN ÖSTERREICH Region: OSTÖSTERREICH WIEN |
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| Organization: UNIVERSITY OF ZURICH | |
| Contact person | Address |
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Name: |
INSTITUTE OF NEUROPATHOLOGY Scmelzbergstrasse 12 8091 ZURICH SCHWEIZ/SUISSE/SVIZZERA Region: |
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Sources: European Commission

