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Projects

ESPRIT

project name: European Stroke Prevention in Reversible Ischaemia Trial

initiating country: The European Union

Framework Programme: FP5 programme area: QoL – Quality of Life and Management of Living Resources

contract/proposal/call number: QLK6-CT-2002-02332

status: active

start date: January 2003 duration: 48 months projected finish date: January 2007

Project Budget

total budget: € 354,798

Participants

Note that the follow people may not represent the full extent of the consortium. FEAST has tried to identify the Australian participants, and their collaborators (or coordinator), within the project. Also note that Australian participation may not necessarily be on a formal level.

name	organisation	state or country
Dr Graeme Hankey	Royal Perth Hospital	WA, Australia

Further information

summary:

Patients who have had a transient is haemic attack or no disabling is haemic stroke of arterial origin have an annual risk of 7 to 12 % for subsequent nonfatal stroke, nonfatal myocardial infarction or death (from all vascular causes) without treatment. The standard treatment acetylsalicylic acid (ASA) prevents only 13% of these events; this is far from ideal. Data from secondary prevention trials in other cerebrovascular diseases suggest that oral anticoagulation (AC) or ASA combined with dipyridamole are more effective in the secondary prevention. Since cerebrovascular disease is one of the major European health problems, especially in the elderly, it is of utmost importance to look for more effective prevention than that by ASA. ESPRIT is a randomised, international, multicoated trial in which three treatments are compared:

a) ASA,

b) ASA combined with dipyridamole

c) AC (INR 2-3). A total of 4500 patients will be enrolled.

Coordinator

Organization name: UNIVERSITY MEDICAL CENTRE UTRECHT
Contact person	Address
Name: Jan VAN GIJN (Prof.)	DEPARTMENT OF NEUROLOGY Heidelberglaan 100 3584CX UTRECHT NEDERLAND Region: WEST-NEDERLAND UTRECHT
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Other participants

Organization: CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE
Contact person	Address
Name: LEYS, Didier (Prof.)	HOPITAL ROGER SALENGRO Rue Emile Laine 59037 LILLE FRANCE Region: NORD - PAS-DE-CALAIS Nord
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Organization: CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS
Contact person	Address
Name: BOGOUSSLAVSKY, Julien (Prof.)	SERVICE DE NEUROLOGIE Rue du Bugnon 46 1011 LAUSANNE SCHWEIZ/SUISSE/SVIZZERA Region:
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Organization: ERASMUS UNIVERSITEIT ROTTERDAM
Contact person	Address
Name: KOUDSTAAL, Peter (Prof.)	ERASMUS UNIVERSITY MEDICAL CENTER Dr. Molewaterplein 50 3015 GE ROTTERDAM NEDERLAND Region: WEST-NEDERLAND ZUID-HOLLAND Groot-Rijnmond
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Organization: GENERAL HOSPITAL SINT JAN AV BRUGGE
Contact person	Address
Name: VANHOOREN, Geert (Dr.)	DEPARTMENT OF NEUROLOGY Ruddershove 10 8000 BRUGGE BELGIQUE-BELGIË Region: VLAAMS GEWEST WEST-VLAANDEREN Brugge
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Organization: HOSPITAL CLINIC BARCELONA
Contact person	Address
Name: CHAMORRO, Angel (Dr.)	NEUROLOGY SERVICE Calle Villaroel 170 08036 BARCELONA ESPAÑA Region: ESTE CATALUÑA Barcelona
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Organization: ROYAL PERTH HOSPITAL
Contact person	Address
Name: HANKEY, Graeme (Dr.)	DEPARTMENT OF NEUROLOGY Wellington Street QA 6001 PERTH Region:
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Organization: SINGAPORE GENERAL HOSPITAL
Contact person	Address
Name: CHEN, Christopher (Dr)	Outram Road 169608 SINGAPOUR Region:
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Organization: STROKE SERVICE PERUGIA
Contact person	Address
Name: RICCI, Stefano	SERVIZIO PER LE MALATTIE CEREBROVASCOLARI Via Guerra, 17 06127 PERUGIA ITALIA Region: CENTRO (I) UMBRIA Perugia
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Organization: TEL AVIV SOURASKY MEDICAL CENTER
Contact person	Address
Name: BORNSTEIN, Natan (Dr.)	DEPARTMENT OF NEUROLOGY Weizman Street 6 64239 TEL AVIV ISRAEL Region:
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Organization: THE CENTRAL SHEFFIELD UNIVERSITY HOSPITALS
Contact person	Address
Name: VENABLES, Graham (Dr.)	ROYAL HALLAMSHIRE HOSPITAL Clossop Road S10 2JF SHEFFIELD UNITED KINGDOM Region: YORKSHIRE AND HUMBERSIDE SOUTH YORKSHIRE
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Organization: UNIVERSIDADE DE LISBOA
Contact person	Address
Name: FERRO, Jose (Prof.)	FACULDADE DE MEDICINA Av. Prof. Egas Moniz 1649 035 LISBOA PORTUGAL Region: CONTINENTE LISBOA E VALE DO TEJO Grande Lisboa
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Organization: UNIVERSITY MEDICAL CENTRE UTRECHT
Contact person	Address
Name: BORNSTEIN, Natan (Dr.)	JULIUS CENTRE Heidelberglaan 100 3508 GA UTRECHT NEDERLAND Region: WEST-NEDERLAND UTRECHT
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Organization: WAGNER JAUREGG HOSPTIAL LINZ
Contact person	Address
Name: AICHNER, Franz (Prof.)	DEPARTMENT OF NEUROLOGY Wagner Jauregg Weg, 15 4020 LINZ ÖSTERREICH Region: WESTÖSTERREICH OBERÖSTERREICH Linz-Wels
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Organization: WESTFAELISCHE WILHELMS - UNIVERSITAET MUENSTER
Contact person	Address
Name: RINGELSTEIN, Bernd (Prof.)	KLINIK UND POLIKLINIK FUER NEUROLOGIE Albert Schweizerstrasse, 33 48129 MUENSTER DEUTSCHLAND Region: NORDRHEIN-WESTFALEN MÜNSTER Münster, Kreisfreie Stadt
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Sources: European Commission

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