Projects
SONOCAPS
project name: Ultrasonic synthesis of oil-filled protein and polysaccharide microcapsules
initiating country: The European Union
Framework Programme: FP7 programme area: MC – People contract type: MCIRSES – Marie Curie International Research Staff Exchange Scheme
contract/proposal/call number: 230779
status: active
start date: January 2009 duration: 24 months projected finish date: January 2011
Keywords
keywords: biodegradable microcapsules; polysaccharide macromonomers
Project Budget
Participants
Note that the follow people may not represent the full extent of the consortium. FEAST has tried to identify the Australian participants, and their collaborators (or coordinator), within the project. Also note that Australian participation may not necessarily be on a formal level.
| name | organisation | state or country |
|---|---|---|
| Maria Letizia Terranova | UTV | Italy |
| Dr Muthupandian Ashokkumar | The University of Melbourne | VIC, Australia |
Further information
summary:
The scientific objective of the research carried out in this International Research Staff Exchange Scheme is the design and synthesis of a novel class of biodegradable microcapsules using the mild chemistry of polysaccharides and proteins, using ultrasound-induced polymerization of macromonomers. Ultrasound induced polymerization of monomers in solution and in emulsions has been widely used in the past but so far has not been applied to polysaccharide macromonomers. In this proposal, we intend to apply this strategy to prepare oil-filled microcapsules by radical polymerisation at the oil/water interface of macromonomers. This approach can be considered as a general method for fabricating polysaccharide- and protein-based hollow microcapsules for application in both drug delivery and food science. Ultrasound will be also used as a technique for encapsulation. Microparticles will be loaded with anti-cancer agents, conventionally used for the clinical treatment of malignancies (e.g., doxorubicin) or innovative therapeutic agents as peptide nucleic acid (PNA).
Participants
UNIVERSITY OF MELBOURNE AUSTRALIA
UNIVERSITY OF BATH UNITED KINGDOM
Source: Cordis
